Nasopharyngeal angiofibroma is a histologically benign but locally aggressive vascular tumor that grows in the back of the nasal cavity. It most commonly affects adolescent males and may grow into fissures of the. Nasoangiofibroma youth is a highly vascularized tumor almost exclusively male adolescents presentation. % represents % of head and. Angiofibroma nasofaring juvenile – Free download as PDF File .pdf), Text File . txt) or read online for free.
|Published (Last):||3 May 2004|
|PDF File Size:||5.67 Mb|
|ePub File Size:||17.2 Mb|
|Price:||Free* [*Free Regsitration Required]|
Thank you for updating your details. Views Read Edit View history. This tumor originates in the lateral wall of the nasal cavity, close to the superior border of the sphenopalatine foramen. Mast cells and T-lymphocytes in juvenile angiofibromas. It is, as the name suggests, very vascular and a biopsy can sometimes be fatal.
The presentation is typically with obstructive symptoms, jugenileand chronic otomastoiditis due to obstruction of the Eustachian tube.
Juvenile nasopharyngeal angiofibroma
No encapsulation was noted [ Figure 4 ]. The main clinical presentation of JNA is unilateral nasal obstruction with or without epistaxis. The blood vessels are slit-like or dilated, organized in clusters and are of different calibers. The exact site of origin is contentious as these masses usually present when they have reached considerable size. Two types of lateral extension in juvenile nasopharyngeal angiofibroma: Any naosfaring with this presentation may be confused with JNA.
This supports the hypothesis that the vascular endothelial cells may become postembryonic undifferentiated mesenchymal cells and can be induced into other mesenchymal nonhemopoitic cell phenotypes.
The prevalence in males may be explained by high androgen receptor AR expression suggesting that JNA is androgen dependent. The presence of prominent flow voids lead to a salt and pepper appearance on most sequences and are characteristic 5,6.
Androgen receptor, juvenile angiofiborma, nasopharyngeal angiofibroma. Case 2 Case 2. They may be locally aggressive. Endoscopic approach is an excellent tool in primary and recurrent JNA, it allows visualisation and precise removal of the lesion. Synonyms or Alternate Spellings: Provisional diagnosis of nasopharyngeal angiofibroma, soft tissue tumor, nasopharyngeal polyp or vascular tumor was made. When diagnosed early the patients are treated with a combination of preoperative embolization and surgical resection providing a good prognosis.
Case 5 Nasofraing 5. Findings are similar to those described above. Sign up for our Email Newsletters.
Although benign, it nasofarinh a locally aggressive tumor and invades the surrounding tissues and even bone through pressure resorption. On examination, it may be seen as a pale reddish-blue mass. Author information Article notes Copyright and License information Disclaimer. Bilateral vascular supply in juvenile nasopharyngeal angiofibromas.
Juvenile nasopharyngeal angiofibroma | Radiology Reference Article |
Diagnosis is arrived at by clinical examination, radiography, nasal endoscopy and specialized imaging techniques anngiofibroma as CT scan and MRI. The infratemporal fossa approach for nasopharyngeal tumors. Type III is a calabash-like massive tumor lobe in the middle cranial fossa.
Supply of these tumours is usually via Clinical examination reveals a firm and friable mass in the nasopharynx and nose.
There is marked contrast enhancement following administration of contrast, reflecting the prominent vascularity. Juvenile nasopharyngeal angiofibroma JNA is a benign neoplasm of the nasopharynx. Loss of expression of GSTM 1 null genotype is seen in this tumor.
Nasopharyngeal angiofibroma – Wikipedia
InFriedberg called it juvenile angiofibroma. It presents as an innocuous, painless, unilateral nasal obstruction with or without epistaxis and rhinorrhea. Pancoast tumor Solitary pulmonary nodule Central lung Peripheral lung Bronchial leiomyoma. JNA is an uncommon benign tumor predominantly affecting adolescent males.
New author database being installed, click here for details. This may be attributed to a rich vasculature and lack of encapsulation. Genetic evidence for an androgen-dependent tumor? Histopathology reveals a fibrocellular stroma with spindle cells and haphazard arrangement of collagen interspersed with an irregular vascular pattern.
Clinically, however, it is obscure with painless, progressive unilateral nasal obstruction being the common presenting symptom with or without epistaxis and rhinorrhea. See staging of juvenile nasopharyngeal angiofibromas.